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By integrating imaging, biochemical, and lipidomic approaches across in situ , in vitro and ex vivo assays, we demonstrate that ORP5 promotes the efficient channeling of PA into TAG and LD storage, while simultaneously preventing its excessive accumulation in mitochondria, and subsequent cardiolipin overload (Supp

Upon -KG insufficiency or treatment by -KG competitors (succinate and ITA), lower TET activity reduces YBX1 transcription and prevents AMPK1 translation

A recent study found that MASLD, hepatic steatosis, and fibrosis are associated with an increased risk of CKD (123)

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Kasamatsu S., Ida T., Koga T., Asada K., Motohashi H., Ihara H., Akaike T

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Some research suggests it may have potential benefits for wound healing and tissue repair